drug repurposing

Computational Strategies to Combat COVID-19: Useful Tools to Accelerate SARS-CoV-2 and Coronavirus Research

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools …

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Various studies exist about the molecular mechanisms of viral infection. However, such information is spread across many publications and it is very …

The fight against COVID-19

The CoVex systems medicine platform allows identifying putative drug targets and drug repurposing candidates to treat COVID-19.

CoVex

A web app for mining the Sars-COV-1/2 virus-host-drug interactome for drug repurposing candidates.

REPO-TRIAL

The EU H2020 project REPO-TRIAL aims at developing an **in silico** approach to optimise the efficacy and precision of drug repurposing trials. To this end we integrated heterogeneous data into a comprehensive interactome of disease-drug-gene interactions (a new diseasome).