cancer

MiRNA-181d Expression Significantly Affects Treatment Responsesto Carmustine Wafer Implantation

BACKGROUND: Standard therapeutic protocols for glioblastoma, themost aggressive type of brain cancer, include surgery followed bychemoradiotherapy. Additionally, carmustine-eluting wafers can beimplanted locally into the resection cavity. OBJECTIVE: …

The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma

The long non-coding RNA (lncRNA) H19 represents a maternally expressed and epigenetically regulated imprinted gene product and is discussed to have either tumor-promoting or tumor-suppressive actions. Recently, H19 was shown to be regulated under …

Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma