Markus List
Head of the Research Group Big Data in Biomedicine
Chair of Experimental Bioinformatics
Technical University of Munich
Markus List heads the group of Big Data in Biomedicine which is part of the Chair of Experimental Bioinformatics at the Technical University of Munich. We are located in the TUM School of Life Sciences in Freising-Weihenstephan.
We develop machine learning models and user-friendly software tools that integrate big heterogeneous (OMICS) data on the network level. Our focus is on next-generation sequencing data where we seek to understand splicing and transcriptional control through histone modifications, DNA methylation, microRNAs, long non-coding and circular RNAs. We leverage the tools and context-specific (e.g. disease-specific) networks we create for applications in systems and network medicine ranging from disease module discovery and endophenotyping to drug repurposing.
Interests
- Integration of multi-omics data
- Transcriptomics and gene regulation
- Epigenetic mechanisms and cell type heterogeneity
- Drug target discovery and repurposing
- (Federated) Machine Learning and Artificial Intelligence
- Systems and Network BioMedicine
Education
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PhD in Health Sciences, 2015
University of Southern Denmark
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MSc in Bioinformatics, 2011
Eberhard-Karls Universität Tübingen
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BSc in Bioinformatics, 2008
Eberhard-Karls Universität Tübingen